A plain directory of Charlotte-based companies with AI at the core of the product, sorted by category. No rankings, and every entry was checked against a source.
By James Pentalow, organizer of Building with AI Charlotte · Published November 10, 2026
AI companies based in Charlotte, NC include Aiwyn (tax and practice software for accounting firms), Fastbreak AI (sports scheduling and operations), Siftwell (member risk analytics for managed care), Field Materials AI (construction purchasing), Botsplash (customer messaging) and Codd AI (a semantic layer for analytics). This page lists 14, by category.
Companies listed14, all based in Charlotte
Categories6, alphabetical within each
Last checkedNovember 10, 2026
The rule for this list is simple. A company has to be based in Charlotte, and AI or machine learning has to be the core of what it sells. We confirmed both from the company's own site, a press release or local tech news. Companies we could not confirm were left out, so this is not a complete census. The order is alphabetical, not a ranking.
Charlotte AI companies at a glance
Company
Category
Focus
Aiwyn
Fintech and accounting
Software for accounting firms
Amissa
Healthcare
Menopause care data for clinicians
Auditrol
Fintech and accounting
Regulatory risk for banks
Botsplash
Sales and messaging
Customer messaging and CRM
Codd AI
Data and developer tools
Semantic layer for analytics
Fastbreak AI
Sports
Sports scheduling and operations
Field Materials AI
Construction
Material purchasing
FlightSuite
Sales and messaging
Coaching for field sales teams
Franzy
Consumer
Franchise matching
Meridian
Real estate
Computer vision property scans
Msg2ai
Sales and messaging
Guest texting for venues
Readalot.ai
Education
Generated stories for kids
SetSale
Sales and messaging
HVAC sales quotes
Siftwell
Healthcare
Member risk analytics
Fintech and accounting AI companies in Charlotte
Fintech and accounting
Aiwyn
What it does: A software platform for accounting firms that covers payments, practice management, client experience and tax, including a tax calculation engine the company describes as AI-native.
Based in: Charlotte (stated in its April 2026 press release)
What it does: A platform that helps banks and other financial institutions manage regulatory risk, using AI to check an institution's data against the rules that apply to it.
What it does: A menopause care platform that turns patient symptom tracking into records for clinicians, with AI used to summarize the data before an appointment.
What it does: Analytics for managed care organizations. Its AI engine combines clinical, social and environmental data to surface member risks and guide outreach.
Sales, marketing and customer messaging AI companies in Charlotte
Sales and messaging
Botsplash
What it does: A customer engagement platform that handles conversations over SMS, chat, voice and email, with AI that answers and qualifies customers and then hands off to a person.
Data and developer tools AI companies in Charlotte
Data and developer tools
Codd AI
What it does: A platform that uses generative AI to turn business knowledge and data metadata into a governed semantic layer for analytics and AI agents.
Real estate and construction AI companies in Charlotte
Construction
Field Materials AI
What it does: Purchasing software for construction firms, with AI that reads vendor quotes, matches delivery slips to purchase orders and checks invoices.
Based in: Charlotte (stated in its August 2026 press release)
Sports, education and consumer AI companies in Charlotte
Sports
Fastbreak AI
What it does: A sports operations platform for leagues, tournaments and clubs, built around a scheduling engine that balances travel, rest, venues and broadcast needs.
What it does: A platform for developing renewable and data center projects. It tracks permits, land, grid connections and financing, and its AI drafts tasks and budgets for a person to approve.
Larger employers in the region work on AI too. These four have publicly documented AI work.
Advocate Health (Charlotte): uses ambient AI for clinical documentation and imaging AI, according to Becker's Hospital Review.
Duke Energy (Charlotte): said in February 2026 that it uses AI tools to spot scams aimed at its customers.
Lowe's (Mooresville): offers Mylow, an AI home improvement assistant for shoppers, and has funded an AI and machine learning faculty position at UNC Charlotte.
Truist (Charlotte): said in June 2026 that many of its recent patents involve AI or machine learning.
How to get listed
If your company is based in Charlotte and AI is the core of the product, tell us and send a link that shows both. We add companies we can confirm, and there is no fee and no ranking. You can also pitch at a meetup. Read the 25-minute pitch template, then check upcoming events for the next date. If you are still looking for a community first, see our guide to AI groups in Charlotte.
Last checked November 10, 2026. Companies move, rename and get acquired, so confirm details on each company's own site. Spot something out of date? Tell us.
Frequently asked questions
What are some AI companies based in Charlotte, NC?
Charlotte-based AI companies include Aiwyn, Fastbreak AI, Siftwell, Field Materials AI, Botsplash and Codd AI. This directory lists 14 companies across fintech, healthcare, sales, data, real estate and consumer products.
How did you decide which companies to include?
A company had to be based in Charlotte and have AI or machine learning at the core of its product. We confirmed both from the company's own site, a press release or local tech news, and left out anything we could not confirm.
Is this a ranking of the best AI startups in Charlotte?
No. The list is alphabetical within each category and does not score or rank companies.
Do large Charlotte employers work on AI too?
Yes. Advocate Health, Duke Energy, Truist and Mooresville-based Lowe's have all described AI work in public sources, which are linked at the bottom of this page.
Building with AI Charlotte is a free monthly meetup at Hygge Coworking in the Belmont neighborhood, with two builder pitches each night. The next one is Wednesday, December 2, 2026.